Facebook_off Twitter_off Pinterest Instagram_off Googleplus_off Youtube_off Emailnewsletter

Welcome to DogHeirs, Where Dogs Are Family! Log in or Sign Up


DogHeirs Tshirts

Mitral Valve Dysplasia - Overview

Dhicon_thumb By DogHeirs Team | March 17, 2011 | Comments (1)

Overview | Symptoms | Treatment | Management

Mitral Valve Dysplasia (MVD) is also known as Mitral Valve Disease, Mitral Valve Disorder, Mitral Valve Malformation, Mitral Dysplasia, Mitral Systolic Murmur, Cardiac Valve Disease (CVD), Endocardiosis, Atrioventricular Valve Endocardiosis, Chronic Degenerative Valvular Disease, Chronic Valvular Disease, Chronic Mitral Valve Insufficiency, Myxomatous Atrioventricular Degeneration, Chronic Valvular Fibrosis, Acquired Mitral Regurgitation or Insufficiency, and Mitral Valve Defect.

Mitral valve diseaseMitral Valve Dysplasia is a condition in which a defect in the mitral valve (the left atrioventricular valve) causes backflow of blood into the left atrium, or mitral regurgitation. Chronic mitral regurgitation leads to volume overload of the left heart, which results in dilatation of the left ventricle and atrium. When mitral regurgitation is severe, cardiac output decreases, which results in signs of cardiac failure. Severe mitral regurgitation can also result in pulmonary venous congestion and left-sided congestive heart failure (CHF). Dilatation of the left-sided chambers predisposes affected animals to arrhythmias. In some cases, malformation of the mitral valve complex causes a degree of valvular stenosis as well as insufficiency.

Mitral valve insufficiency is age- and breed-related, with older, small-breed dogs demonstrating a higher incidence. There is also a slight predisposition among male dogs. This disease is the most common acquired cardiac disease in older dogs, affecting over one third of dogs greater than 10 years of age. In some breeds however, mitral insufficiency develops at a much younger age, due to an inherited predisposition for this disorder. In fact, in some breeds, abnormal development (dysplasia) of the valve has been identified in embryos.

Mitral valve murmurs are graded from the mildest and least audible to the loudest and most turbulent. The loudness of the murmur usually indicates the severity of the disease.

Grade 1:  Murmur can be heard with a stethoscope in a quiet room.

Grade 2:  Can be consistently heard with the stethoscope.

Grade 3:  Murmurs are louder and are heard as soon as the stethoscope is applied.

Grade 4: Quite loud, and the vibration can be felt with fingertips without a stethoscope.

Grade 5:  Murmur is louder, with a precordial "trill".

Grade 6:  So loud it can be heard with the stethoscope removed from the chest, or even without using the stethoscope.

Age at onset: Abnormal heart morphologies have been seen observed during embryonic stages, however this disease is more commonly seen in dogs over the age of 10 years.

Breeds Affected: Mitral valve disease is the most common heart disorder in older dogs of all breeds. In general, small breeds are most often affected and some studies show a greater incidence in males than in females

  • Beagle
  • Boston terrier
  • Bull Terrier
  • Cairn terrier
  • Cavalier King Charles Spaniel
  • Chihuahua
  • Cocker Spaniel
  • Dachshund
  • German Shepherd
  • Golden Retriever
  • Great Dane
  • Labrador Retriever
  • Miniature Poodle
  • Miniature Pinscher
  • Miniature Schnauzer
  • Papillon
  • Pekingese
  • Standard Poodle
  • Toy Poodle
  • Whippet
  • Yorkshire Terrier

Symptoms: Dogs have a an increasingly loud heart murmer, abnormal heart rhythm, reduced tolerance for exercise, difficulties in breathing, or a cough at night or at rest. They may faint, show weakness, or collapse.

Genetics of Mitral Valve Dysplasia: The genetics of mitral valve dysplasia are not well understood yet, however research studies indicate it is an inherited trait.

Mitral Valve Dysplasia in Humans: Mitral valve disease is a genetic disorder in humans that is highly similar to the disease in dogs. In addition, Ebstein's anomaly in humans is thought to be share similarities to tricuspid valve dysplasia.


Below is a video produced by the American College of Veterinary Internal Medicine featuring Teresa DeFrancesco, DVM, DACVIM (Cardiology), DACVECC, speaking with Steve Dale on the topic of Mitral Valve Disease in dogs.

Copyright 2015 DogHeirs. All Rights Reserved.

View more articles in: Mitral Valve Dysplasia

You may also like

Elephant and dog best friends love playing in the water together (VIDEO)

Bubbles the elephant and Bella the Labrador Retriever are best friends and have bonded over their love of water. They love to swim and play in the river together. Bubbles wants to spend time with Bella and makes it a game for Bella to climb and jump off her back.   Bubbles was adopted as an ivory orphan (her parents killed for their ivory by poachers) by Myrtle Beach Safari in 1983.   Related: Baby...
Read more

Hidden camera catches clever Beagle stealing chicken nuggets (VIDEO)

Lucy the Beagle has figured out that there are tasty things in the toaster oven and knows how to get them. After a roast disappeared a few weeks earlier, her guardian Rodd Scheinerman decided to set up a sting operation. He wrote on YouTube, "A few weeks before she took a roast out of the oven that had been cooking for a few hours… So I set her up. I put some nuggets in the...
Read more

Golden Retriever guards owner's bicycle and then does the most incredible thing (VIDEO)

A Golden Retriever named Li Li has become something of a local celebrity in China for his habit of guarding his guardian's bicycle. Li Li's guardian, Luo Wencong does not need to buy a bike lock as Li L, keeps such a close eye on it for him. "Whenever I park up my bike, he wraps his forelegs around it to prevent it from being stolen," says Luo. Luo says Li Li is very intelligent...
Read more

Canine Hip Dysplasia: Symptoms, Diagnosis, Treatment and Prevention

Hip dysplasia is one of the most common skeletal diseases in dogs and affects millions of dogs worldwide. As the disease progresses, a dog's hip joints degenerate, causing increased pain and mobility issues for the dog. If left untreated, a dog will eventually be unable to use his/her hind legs and suffer extreme pain. However, the vast majority of dogs with hip dysplasia can lead full and active lives if the disease is diagnosed early...
Read more

Golden Retriever puppy delighted to see toddler (VIDEO)

A 2-month-old Golden Retriever puppy is delighted to meet an 8-month-old baby who has come over for a visit!   Related: Baby and dog share a playful moment Baby learns to chew from puggles Sweet dog helps teach baby to crawl
Read more

Comments on this Article

Wow. I hadn't realized how many breeds are affected by this disease.

» View all comments

Add Your Comment!

Log in to leave a comment or Create an account

Spring Sale on T-Shirts

Must See

Questions About Mitral Valve Dysplasia

Follow DogHeirs

Also find us on: DogHeirs on Twitter DogHeirs on Pinterest DogHeirs on Instagram DogHeirs on Google+

Copyright 2015 DogHeirs