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Adverse Reactions to Convenia

Dhicon_thumb By DogHeirs Team | June 06, 2011 | Answers (5)


Has your pet experienced an adverse reaction to Convenia? Please share details on the breed, age and number of times your pet was exposed to Convenia.

Karen's recent post on Convenia inspired us to research this drug further and investigate other adverse reactions to this drug.

Convenia is an antibiotic. It is often used for the treatment of skin infection in cats and dogs, but can be used for other conditions. Convenia's benefit of use is that it provides a whole course of treatment in a single injection, as opposed to more conventional daily oral antibiotics.

The safety warning for Convenia states: Convenia is not for use in dogs or cats with a history of allergic reactions to penicillins or cephalosporins. Similar to other cephalosporins, side effects for both dogs and cats include vomiting, diarrhea, decreased appetite/anorexia and lethargy. The safety of CONVENIA has not been determined in lactating or breeding animals, or in animals less than four months of age.

Convenia was tested on 320 dogs and 291 cats, with the adverse reactions reported as above. However, in markets outside of the USA, additional adverse reactions were reported after Convenia was approved for use in cats and dogs. These adverse reactions included:

  • death
  • tremors/ataxia
  • seizures
  • anaphylaxis
  • acute pulmonary edema
  • facial edema
  • injection site reactions (alopecia, scabs, necrosis, and erythema)
  • hemolytic anemia
  • salivation
  • pruritus
  • lethargy
  • vomiting
  • diarrhea
  • inappetance

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Answers To This Question

My sharpei passed away yesterday, just a few hours after the vet gave her a shot of Convenia. I wish I had look this up before they injected her with that. I'm heart broken now. I hope something is done to investigate this antibiotic further.
Friday afternoon 09/27/13 my dog Frankie went outside to do his business, he was fine. About 30 minutes after he came in he started vomiting. That evening he seemed to be okay. Saturday morning I woke up to him shaking, breathing heavily and weak. I scooped him up in my arms and we rushed him to the vet. The vet did blood, serum chemistries and then fluids. The vet wasn't sure what was wrong but his white blood count was slightly elevated. He asked if I could give him antibiotics, I said, yes. He came out with Frankie and said "we gave him an antibiotic that will last for 7 days so you don't have to give him any". This is new to me... I took my boy home, he progressively got weaker and weaker. We thought it was because the antibiotic were tiring him out. I carried him into each room assuring him tomorrow would be better. The vet did advise us that he would be out of it for a day or two. I woke up at 4AM to my dog yelping in pain having a seizure. He was in complete shock. He kept having continual smaller seizures. We got him to the 24 hour vet and he went into a full seizure. He was suffering greatly. We had to put him to sleep... He was on Covenia... all the negative side effects match up to what he went through. My heart is broken... Had I known of this drug before it was administered, I would have never let them use it.
My beautiful bernese mtn dog Angel had knee surgery Sept 25, 2012. He was given an injection of Covenia because he would not take large antibiotic pills by mouth (even with food, pill pockets, etc). He worked hard to overcome the challenge of the operation, was doing well...on Nov 25 suddenly had trouble breathing, fell over...rushed to hospital, was put on oxygen, antibiotics for pneumonia, iv, etc...many tests done, he got progressivly worse, heart rate increased, more meds given....I was told he did NOT have pneumonia. they did not know and could not figure out what was wrong...only that he was a "very sick dog"...offered no hope for recovery. I had to put my beloved dog to sleep on Nov 26th, 2012. I am devastated by the loss. this is a dog who recieved shots every 3 wks for addisons...he never gave the vet a problem with that...but when she injected him with CONVENIA he reacted very badly, almost bit her...she was shocked by as was I. This is a very gentle loving dog. He was angry about that shot, he refused to come in the house at night and would not let me put the protective cone around his neck, growling at me as well....he never did that, ever! Convenia? interesting name....as in convenient? Stay away from it...do not allow it to be used on your animals. I know it killed him. I know nothing can bring him back now...but I will never forget the name of this medicine...never. I read that it stays in the system over 2 months and there is no way to get rid of it. once administered, there is no turning back. I wish I had known this before. He would have been better off with an amputated leg, than this end result. I am heart sick over it.
My Maltese Sammy was injected with Convenia on April 27, 2012. A few short hours later his demeanor completely changed - from bright and happy to lethargic and stumbling. He did not have a skin infection, but instead had coughing/vomiting symptoms that resulted in this shot being given. Within a few hours, Sammy passed away - 4 vets examined him prior to his passing and couldn't figure out what was wrong with him. After much research and in speaking with the vet that administered this drug, it is strongly suspected he had an adverse reaction to Convenia. I wish I had known about this drug prior to it being given to him.
My vet has given this shot to my cat at least 3-4 times as i can't get liquid meds down him w/o getting all clawed up. I haven't seen a problem yet but now i will be worried if he gets sick again. I know he now has what i think is a hot spot, he pulled all the hair out & started licking it raw since the last shot he had. I am hoping now that there is no connection. He's inside so i know he didn't get anything from outside.
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